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Double-stranded RNA viruses
・ Double-stranded uracil-DNA glycosylase
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Double-stranded RNA viruses : ウィキペディア英語版
Double-stranded RNA viruses

Double-stranded (ds) RNA viruses are a diverse group of viruses that vary widely in host range (humans, animals, plants, fungi, and bacteria), genome segment number (one to twelve) and virion organization (T-number, capsid layers or turrets). Members of this group include the rotaviruses, known globally as a common cause of gastroenteritis in young children, and bluetongue virus, an economically important pathogen of cattle and sheep.
Of these families, the ''Reoviridae'' is the largest and most diverse in terms of host range.
In recent years the increasing knowledge of virus particle assembly, virus-cell interactions, and viral pathogenesis allow approaches for the development of novel antiviral strategies or agents.
==Taxonomy==

Viruses with dsRNA genomes are currently grouped into a number of families, unassigned genera and species.
Three families infect fungi: ''Totiviridae'', ''Partitiviridae'' and ''Chrysoviridae''. These families have monopartite, bipartite and quadripartite genomes respectively. They are typically isometric particles 25–50 nanometers in diameter. Based on sequence similarity of the RNA dependent RNA polymerase, the partitiviruses are probably derived from a totivirus ancestor. A fourth family — ''Alternaviridae'' — has recently been described also with quadripartite genome.
Hypoviruses are mycoviruses (fungal viruses) with unencapsidated dsRNA genomes. They may have common ancestry with plant positive strand RNA viruses in supergroup 1 with potyvirus lineages. respectively〔
A new clade (as yet unnamed) of six viruses infecting filamentous fungi has been reported.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Double-stranded RNA viruses」の詳細全文を読む



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